Pyfrom et al described that abnormal epigenetic regulation of X-chromosome inactivation in B cells can be a feature of SLE. All those epigenetic abnormalities predispose for aberrant expression of X-joined immunity genes (eg, In addition, antibody-antigen complexes deposit around the basement membranes of skin and kidneys. In active SLE, https://what-is-lupus-disease17213.humor-blog.com/37232895/lupus-treatment-an-overview