Can Alcohol Cause Appendicitis? Appendicitis occurs when the appendix becomes inflamed, often due to blockages or infections. While alcohol is not a direct cause of appendicitis, excessive consumption can weaken the immune system, making the body more susceptible to infections that might trigger appendix inflammation. Chronic alcohol use may also lead to gastrointestinal issues, indir... https://healthstrives.com/can-alcohol-cause-appendicitis/