The recognized influence of these PTMs on ATXN2’s function and SCA2 pathogenesis continues to be confined. In other polyQ diseases, various experiments instructed that proteolytic cleavage of polyQ proteins could Enjoy a significant purpose in pathogenesis [36, 45]. Aligned with this strategy, the presence of the enriched forty two kDa fragment https://rotenone43219.get-blogging.com/28778567/not-known-facts-about-sdz-220-040