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DS39201083 had a novel bicyclic skeleton and was a more powerful analgesic than conolidine, as discovered inside the acetic acid-induced writhing examination and formalin check in ddY mice. The compound confirmed no agonist activity in the mu opioid receptor. Increasing locomotor physical exercise is a standard CNS reaction to opioids http://judahvodsg.ampedpages.com/Conolidine-Things-To-Know-Before-You-Buy-34790137


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